A.1 Motivation For what purpose was the dataset created? As an affiliated dataset, we created MIMIC-CXR-VQA to provide a benchmark for medical visual question answering systems. Who created the dataset (e.g., which team, research group) and on behalf of which Who funded the creation of the dataset? This work was (partially) supported by Microsoft Research Asia, Institute of Information & Communications Technology Planning & Evaluation (IITP) grant (No.2019-0-00075, RS-2022-00155958), National Research Foundation of Korea (NRF) grant (NRF-2020H1D3A2A03100945), and the Korea Health Industry Development Institute (KHIDI) What do the instances that comprise the dataset represent (e.g., documents, photos, EHRXQA contains natural questions and corresponding SQL/NeuralSQL queries (text). How many instances are there in total (of each type, if appropriate)? In EHRXQA, there are about 46.2K instances (16,366 image-related samples, 16,529 table-related samples, and 13,257 image+table-related samples).

The rapid expansion of asynchronous remote care has intensified provider workload, creating demand for AI systems that can assist clinicians in managing patient queries more efficiently. The MEDIQA-WV 2025 shared task addresses this challenge by focusing on generating free-text responses to wound care queries paired with images. In this work, we present two complementary approaches developed for the English track. The first leverages a mined prompting strategy, where training data is embedded and the top-k most similar examples are retrieved to serve as few-shot demonstrations during generation. The second approach builds on a metadata ablation study, which identified four metadata attributes that consistently enhance response quality. We train classifiers to predict these attributes for test cases and incorporate them into the generation pipeline, dynamically adjusting outputs based on prediction confidence. Experimental results demonstrate that mined prompting improves response relevance, while metadata-guided generation further refines clinical precision. Together, these methods highlight promising directions for developing AI-driven tools that can provide reliable and efficient wound care support.

This study demonstrates that incorporating a consistency heuristic into the point-matching algorithm \cite{yerebakan2023hierarchical} improves robustness in matching anatomical locations across pairs of medical images. We validated our approach on diverse longitudinal internal and public datasets spanning CT and MRI modalities. Notably, it surpasses state-of-the-art results on the Deep Lesion Tracking dataset. Additionally, we show that the method effectively addresses landmark localization. The algorithm operates efficiently on standard CPU hardware and allows configurable trade-offs between speed and robustness. The method enables high-precision navigation between medical images without requiring a machine learning model or training data.

Graph Retrieval Augmented Generation (GraphRAG) effectively enhances external knowledge integration capabilities by explicitly modeling knowledge relationships, thereby improving the factual accuracy and generation quality of Large Language Models (LLMs) in specialized domains. However, existing methods suffer from two inherent limitations: 1) Inefficient Information Aggregation: They rely on a single agent and fixed iterative patterns, making it difficult to adaptively capture multi-level textual, structural, and degree information within graph data. 2) Rigid Reasoning Mechanism: They employ preset reasoning schemes, which cannot dynamically adjust reasoning depth nor achieve precise semantic correction. To overcome these limitations, we propose Graph Counselor, an GraphRAG method based on multi-agent collaboration. This method uses the Adaptive Graph Information Extraction Module (AGIEM), where Planning, Thought, and Execution Agents work together to precisely model complex graph structures and dynamically adjust information extraction strategies, addressing the challenges of multi-level dependency modeling and adaptive reasoning depth. Additionally, the Self-Reflection with Multiple Perspectives (SR) module improves the accuracy and semantic consistency of reasoning results through self-reflection and backward reasoning mechanisms. Experiments demonstrate that Graph Counselor outperforms existing methods in multiple graph reasoning tasks, exhibiting higher reasoning accuracy and generalization ability. Our code is available at https://github.com/gjq100/Graph-Counselor.git.

While some metrics cover clinical entities and their relations[9, 11], generally Several evaluation metrics have been developed recently to scoring metrics do not explicitly capture the textual mention automatically assess the quality of generative AI reports for differences in the anatomy, laterality and severity. Further, chest radiographs based only on textual information using phrasal grounding of the findings in terms of anatomical localization lexical, semantic, or clinical named entity recognition methods. in images is not exploited in the quality scoring. In this paper, we develop a new method of report quality In this paper, we propose a metric that captures both finegrained evaluation by first extracting fine-grained finding patterns textual descriptions of findings as well as their phrasal capturing the location, laterality, and severity of a large number grounding information in terms of anatomical locations in images. of clinical findings. We then performed phrasal grounding We present results that compare this evaluation metric to localize their associated anatomical regions on chest radiograph to other textual metrics on a gold standard dataset derived images. The textual and visual measures are then combined from MIMIC collection of chest X-rays and validated reports, to rate the quality of the generated reports. We present to show its robustness and sensitivity to factual errors.

Advancing representation learning in specialized fields like medicine remains challenging due to the scarcity of expert annotations for text and images. To tackle this issue, we present a novel two-stage framework designed to extract high-quality factual statements from free-text radiology reports in order to improve the representations of text encoders and, consequently, their performance on various downstream tasks. In the first stage, we propose a \textit{Fact Extractor} that leverages large language models (LLMs) to identify factual statements from well-curated domain-specific datasets. In the second stage, we introduce a \textit{Fact Encoder} (CXRFE) based on a BERT model fine-tuned with objective functions designed to improve its representations using the extracted factual data. Our framework also includes a new embedding-based metric (CXRFEScore) for evaluating chest X-ray text generation systems, leveraging both stages of our approach. Extensive evaluations show that our fact extractor and encoder outperform current state-of-the-art methods in tasks such as sentence ranking, natural language inference, and label extraction from radiology reports. Additionally, our metric proves to be more robust and effective than existing metrics commonly used in the radiology report generation literature. The code of this project is available at \url{https://github.com/PabloMessina/CXR-Fact-Encoder}.

Electronic Health Records (EHRs), which contain patients' medical histories in various multi-modal formats, often overlook the potential for joint reasoning across imaging and table modalities underexplored in current EHR Question Answering (QA) systems. In this paper, we introduce EHRXQA, a novel multi-modal question answering dataset combining structured EHRs and chest X-ray images. To develop our dataset, we first construct two uni-modal resources: 1) The MIMIC-CXR-VQA dataset, our newly created medical visual question answering (VQA) benchmark, specifically designed to augment the imaging modality in EHR QA, and 2) EHRSQL (MIMIC-IV), a refashioned version of a previously established table-based EHR QA dataset. By integrating these two uni-modal resources, we successfully construct a multi-modal EHR QA dataset that necessitates both uni-modal and cross-modal reasoning. To address the unique challenges of multi-modal questions within EHRs, we propose a NeuralSQL-based strategy equipped with an external VQA API. This pioneering endeavor enhances engagement with multi-modal EHR sources and we believe that our dataset can catalyze advances in real-world medical scenarios such as clinical decision-making and research. EHRXQA is available at https://github.com/baeseongsu/ehrxqa.

Cerebral Microbleeds (CMBs) are chronic deposits of small blood products in the brain tissues, which have explicit relation to various cerebrovascular diseases depending on their anatomical location, including cognitive decline, intracerebral hemorrhage, and cerebral infarction. However, manual detection of CMBs is a time-consuming and error-prone process because of their sparse and tiny structural properties. The detection of CMBs is commonly affected by the presence of many CMB mimics that cause a high false-positive rate (FPR), such as calcification and pial vessels. This paper proposes a novel 3D deep learning framework that does not only detect CMBs but also inform their anatomical location in the brain (i.e., lobar, deep, and infratentorial regions). For the CMB detection task, we propose a single end-to-end model by leveraging the U-Net as a backbone with Region Proposal Network (RPN). To significantly reduce the FPs within the same single model, we develop a new scheme, containing Feature Fusion Module (FFM) that detects small candidates utilizing contextual information and Hard Sample Prototype Learning (HSPL) that mines CMB mimics and generates additional loss term called concentration loss using Convolutional Prototype Learning (CPL). The anatomical localization task does not only tell to which region the CMBs belong but also eliminate some FPs from the detection task by utilizing anatomical information. The results show that the proposed RPN that utilizes the FFM and HSPL outperforms the vanilla RPN and achieves a sensitivity of 94.66% vs. 93.33% and an average number of false positives per subject (FPavg) of 0.86 vs. 14.73. Also, the anatomical localization task further improves the detection performance by reducing the FPavg to 0.56 while maintaining the sensitivity of 94.66%.

The disease is a core concept in the medical field, and the task of normalizing disease names is the basis of all disease-related tasks. However, due to the multi-axis and multi-grain nature of disease names, incorrect information is often injected and harms the performance when using general text data augmentation techniques. To address the above problem, we propose a set of data augmentation techniques that work together as an augmented training task for disease normalization. Our data augmentation methods are based on both the clinical disease corpus and standard disease corpus derived from ICD-10 coding. Extensive experiments are conducted to show the effectiveness of our proposed methods. The results demonstrate that our methods can have up to 3\% performance gain compared to non-augmented counterparts, and they can work even better on smaller datasets.